Autoimmune Encephalitis-A Diagnostic Challenge for the Neurologist

Objective Autoimmune encephalitis, is a clinically challenging entity with varied neurological presentations. As autoimmune serology negative in over 50% cases, our objective was to prioritise the use of electroencephalography supported by MRI Brain or PET–CT imaging make definitive diagnosis encephalitis. Background encephalitis consequence an antibody mediated neuronal damage caused cell surface antigens. However, assays can be early stages disease. Hence, we suggest electroencephalogram along brain PET-CT scans avoid diagnostic delays. Design/Methods During span four years [2018–2022] retrospective review case records 50 patients and non-autoimmune were compared. Besides clinical examination, serum cerebrospinal fluid viral assay, electroencephalogram, Magnetic Resonance FDG-PET- CT used confirm diagnosis. Results 60% seronegative 40 % seropositive group while 90% 10% group. Electroencephalography abnormal all cases 100% [50/50] 80% [40/50] In revealed evidence limbic FDG remaining 20%. 10%. Conclusions electroencephalographic abnormalities enabled [p value <0.001]. While electroencephalography, as sample size small further studies are needed these findings.